PXD041416 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling of eIF3a conditional knockout mice |
Description | In this study, a Cre-loxP system was used to generate eIF3a conditional knockout mice. Tandem mass tag (TMT) labeling with LC-MS/MS analysis was used to identify differentially expressed proteins (DEPs) in fat, lungs, skin, and spleen tissue of the eIF3a knockout mice and controls. Bioinformatics analysis was then used to explore the functions and molecular signaling pathways of these protein landscapes. |
HostingRepository | PRIDE |
AnnounceDate | 2023-07-20 |
AnnouncementXML | Submission_2023-07-20_11:55:12.190.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | WeiZhuo |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-04-09 05:55:48 | ID requested | |
⏵ 1 | 2023-07-20 11:55:13 | announced | |
2 | 2023-11-14 09:03:36 | announced | 2023-11-14: Updated project metadata. |
Publication List
Zhuo W, Chen J, Jiang S, Zheng J, Huang H, Xie P, Li W, Lei M, Yin J, Gao Y, Liu Z, Proteomic profiling of eIF3a conditional knockout mice. Front Mol Biosci, 10():1160063(2023) [pubmed] |
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP) |
submitter keyword: eIF3a, proteomics, knockout mice, protein landscape, oxidative stress |
Contact List
ZhaoqianLiu |
contact affiliation | Xiangya Hospital, Central South University |
contact email | zqliu@csu.edu.cn |
lab head | |
WeiZhuo |
contact affiliation | csu |
contact email | mvp0811@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041416 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041416
- Label: PRIDE project
- Name: Proteomic profiling of eIF3a conditional knockout mice