PXD041374-1

PXD041374 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TAP-MS of human Integrator subunits INTS10 and INTS13
Description	Using a combination of proteomics, interaction studies and structural characterization we show that the INTS10-13-14 module of INT binds several transcriptional regulators and gene-specific transcription factors, whichcould form the molecular basis for a part of INT's gene specificity.
HostingRepository	PRIDE
AnnounceDate	2024-06-27
AnnouncementXML	Submission_2024-06-27_02:36:44.470.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kevin Sabath
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-06 04:40:06	ID requested
⏵ 1	2024-06-27 02:36:45	announced
2	2024-10-22 06:47:39	announced	2024-10-22: Updated project metadata.

Publication List

Sabath K, Nabih A, Arnold C, Moussa R, Domjan D, Zaugg JB, Jonas S, Basis of gene-specific transcription regulation by the Integrator complex. Mol Cell, 84(13):2525-2541.e12(2024) [pubmed]
10.1016/j.molcel.2024.05.027;

Sabath K, Nabih A, Arnold C, Moussa R, Domjan D, Zaugg JB, Jonas S, Basis of gene-specific transcription regulation by the Integrator complex. Mol Cell, 84(13):2525-2541.e12(2024) [pubmed]

10.1016/j.molcel.2024.05.027;

Keyword List

submitter keyword: Human, Integrator, TAP-MS

submitter keyword: Human, Integrator, TAP-MS

Contact List

Stefanie Jonas
contact affiliation	Institute of Molecular Biology and Biophysics, ETH Zurich,Otto-Stern-Weg 5, CH-8093, Zurich, Switzerland
contact email	Stefanie.Jonas@mol.biol.ethz.ch
lab head
Kevin Sabath
contact affiliation	ETH Zurich
contact email	Kevin.sabath@mol.biol.ethz.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD041374
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD041374

PRIDE project URI

Repository Record List

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