PXD041374 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | TAP-MS of human Integrator subunits INTS10 and INTS13 |
Description | Using a combination of proteomics, interaction studies and structural characterization we show that the INTS10-13-14 module of INT binds several transcriptional regulators and gene-specific transcription factors, whichcould form the molecular basis for a part of INT's gene specificity. |
HostingRepository | PRIDE |
AnnounceDate | 2024-06-27 |
AnnouncementXML | Submission_2024-06-27_02:36:44.470.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Kevin Sabath |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos; Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-04-06 04:40:06 | ID requested | |
⏵ 1 | 2024-06-27 02:36:45 | announced | |
Publication List
Sabath K, Nabih A, Arnold C, Moussa R, Domjan D, Zaugg JB, Jonas S, Basis of gene-specific transcription regulation by the Integrator complex. Mol Cell, 84(13):2525-2541.e12(2024) [pubmed] |
10.1016/j.molcel.2024.05.027; |
Keyword List
submitter keyword: Human, Integrator, TAP-MS |
Contact List
Stefanie Jonas |
contact affiliation | Institute of Molecular Biology and Biophysics, ETH Zurich,Otto-Stern-Weg 5, CH-8093, Zurich, Switzerland |
contact email | Stefanie.Jonas@mol.biol.ethz.ch |
lab head | |
Kevin Sabath |
contact affiliation | ETH Zurich |
contact email | Kevin.sabath@mol.biol.ethz.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD041374 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041374
- Label: PRIDE project
- Name: TAP-MS of human Integrator subunits INTS10 and INTS13