PXD041254 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Alternative mRNA splicing controls functions of the human H3K27 demethylase UTX/KDM6A |
Description | The UTX/KDM6A gene encodes the UTX histone H3K27 demethylase, which plays an important role in mammalian development and is frequently mutated in cancers and particularly, in urothelial cancers. Using BioID technique, we explored the interactome of different UTX isoforms. |
HostingRepository | PRIDE |
AnnounceDate | 2024-01-28 |
AnnouncementXML | Submission_2024-01-28_09:50:03.169.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Marc Timmers |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-03-31 07:08:29 | ID requested | |
⏵ 1 | 2024-01-28 09:50:04 | announced | |
Publication List
Fotouhi O, Nizamuddin S, Falk S, Schilling O, Kn, ΓΌ, chel-Clarke R, Biniossek ML, Timmers HTM, Alternative mRNA Splicing Controls the Functions of the Histone H3K27 Demethylase UTX/KDM6A. Cancers (Basel), 15(12):(2023) [pubmed] |
10.3390/cancers15123117; |
Keyword List
submitter keyword: Isoforms, KDM6A,Bladder cancer |
Contact List
Marc Timmers |
contact affiliation | German cancer research center (DKFZ), Germany |
contact email | m.timmers@dkfz-heidelberg.de |
lab head | |
Marc Timmers |
contact affiliation | German Cancer Consortium (DKTK), partner site Freiburg German Cancer Research Center (DKFZ) Foundation under Public Law c/o Department of Urology Zentrale Klinische Forschung (ZKF) Medical Center-University of Freiburg Breisacher Str. 66, 79106 Freiburg, Germany |
contact email | m.timmers@dkfz-heidelberg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD041254 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041254
- Label: PRIDE project
- Name: Alternative mRNA splicing controls functions of the human H3K27 demethylase UTX/KDM6A