PXD041242-3

PXD041242 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Convergence of distinct RNA-silencing pathways on GW182/Tnrc6
Description	The RNA-binding protein Trim71/Lin41 is a phylogenetically conserved developmental regulator that functions in mammalian stem cell reprogramming, brain development and cancer. Trim71 recognizes target mRNAs through hairpin motifs and silences them through molecular mechanisms that await identification. Deposited data are mass spectrometry data from immunoprecipitation experiments with endogenously tagged Tnrc6a. Experiments are carried out in mouse embryonic stem cells (mESCs) in the presence and absence of RNase A.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:52:05.114.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daniel Hess
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-31 01:38:50	ID requested
1	2023-07-04 06:52:26	announced
2	2023-11-14 07:02:26	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:52:05	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/J.MOLCEL.2023.06.001;

10.1016/J.MOLCEL.2023.06.001;

Keyword List

submitter keyword: Trim71 Ago2 Tnrc6a RNA silencing

submitter keyword: Trim71 Ago2 Tnrc6a RNA silencing

Contact List

Helge Grosshans
contact affiliation	Multicellular Systems Friedrich Miescher Institute for Biomedical Research
contact email	helge.grosshans@fmi.ch
lab head
Daniel Hess
contact affiliation	Friedrich Miescher Institute for Biomedical Research
contact email	dhess@fmi.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041242
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041242

PRIDE project URI

Repository Record List

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