PXD041156 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Clients of membrane-bound PDI family members |
Description | The client-specificity of TMX3, TMX4 and TMX5 in cellula, was assessed by expressing mutant forms of the enzymes, where the last cysteine residue of the TMX’s CXXC catalytic sites has been mutated to alanine, which stabilizes the mixed disulfide that oxidoreductases establish with clients. Clients remain disulfide-bonded to the oxidoreductase and are identified upon co-immunoprecipitation and mass spectrometry analyses. |
HostingRepository | PRIDE |
AnnounceDate | 2023-06-12 |
AnnouncementXML | Submission_2023-06-12_07:27:58.325.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD041156 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | ManfredoQuadroni |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-03-28 00:21:17 | ID requested | |
⏵ 1 | 2023-06-12 07:27:58 | announced | |
2 | 2023-11-14 09:01:05 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: trapping mutants, Endoplasmic reticulum,Oxidoreductases, mixed disulfides |
Contact List
MaurizioMolinari |
contact affiliation | Institute for Research in Biomedicine, Via Chiesa 5, 6500 Bellinzona, Switzerland |
contact email | Maurizio.molinari@irb.usi.ch |
lab head | |
ManfredoQuadroni |
contact affiliation | University of Lausanne |
contact email | manfredo.quadroni@unil.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD041156 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041156
- Label: PRIDE project
- Name: Clients of membrane-bound PDI family members