PXD041036 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Interaction of TiO2 nanoparticles with lung fluid proteins and the resulting macrophage inflammatory response |
| Description | Inhalation is a major nanoparticle exposure pathway. Following inhalation, nanoparticles first interact with the lung lining fluid, a complex mixture of proteins, lipids, and mucins. We measure the concentration and composition of lung fluid proteins adsorbed on the surface of titanium dioxide (TiO2) nanoparticles. Using proteomics, we find that lung fluid results in a unique protein corona on the surface of the TiO2 nanoparticles. |
| HostingRepository | PRIDE |
| AnnounceDate | 2023-11-10 |
| AnnouncementXML | Submission_2023-11-10_06:40:54.225.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD041036 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | KarstenPoulsen |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-03-22 14:56:30 | ID requested | |
| ⏵ 1 | 2023-11-10 06:40:54 | announced | |
| 2 | 2023-11-14 08:28:34 | announced | 2023-11-14: Updated project metadata. |
| 3 | 2024-10-22 06:13:54 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
| submitter keyword: Titanium dioxide, Bronchoalveolar lavage, nanoparticles, inhalation,Murine, Protein Corona |
Contact List
| ChristinePayne |
|---|
| contact affiliation | Principal Investigator |
| contact email | christine.payne@duke.edu |
| lab head | |
| KarstenPoulsen |
|---|
| contact affiliation | Duke University |
| contact email | karsten.poulsen@duke.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD041036 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041036
- Label: PRIDE project
- Name: Interaction of TiO2 nanoparticles with lung fluid proteins and the resulting macrophage inflammatory response
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