PXD040965-1
PXD040965 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A Proteomic Approach to Distinguish Leptomeningeal Metastasis in Lung Adenocarcinoma Patients |
| Description | Based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) investigation of cere-brospinal fluid (CSF), we prospectively characterized proteins in CSF samples of 36 lung adeno-carcinoma patients, including 19 LM patients and 17 non-LM patients. We identified 290 signifi-cantly differentially expressed proteins (DEPs). In this study, we applied proteomic methods to develop a model to assist diagnosis of LM in lung adenocarcinoma cancer and identified an important biomarker, TSP-2. |
| HostingRepository | iProX |
| AnnounceDate | 2023-03-20 |
| AnnouncementXML | Submission_2023-08-31_19:19:04.637.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chuan Jin |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-03-19 20:09:33 | ID requested | |
| ⏵ 1 | 2023-08-31 19:19:04 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Lung adenocarcinoma, Leptomeningeal metastasis, Biomarkers, Cerebrospinal fluid, LC-MS/MS |
Contact List
| Xiaolei Wu | |
|---|---|
| contact affiliation | Tianjin Key Laboratory of Clinical Multiomics |
| contact email | xiaolei.wu@proteint.com |
| lab head | |
| Chuan Jin | |
| contact affiliation | Tianjin Key Laboratory of Clinical Multiomics |
| contact email | seq@proteint.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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