PXD040930-1

PXD040930 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human Pancreatic Ductal Adenocarcinoma (PDAC), LC-MS/MS
Description	The aim of the study was to characterize a common molecular mechanism for paclitaxel resistance in Patu-T and Suit-2.028 PDAC cell lines. Despite the ATP-binding cassette (ABC) trasnsporters were already shown to be involved in various chemo-resistant forms of cancers but not in PDAC, the most likely impact of ABCB1 overexpression in PDAC cell models was taken into account in this dataset.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-26_09:15:32.124.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD040930
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Francesco Finamore
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-17 02:43:12	ID requested
⏵ 1	2024-01-26 09:15:33	announced
2	2024-10-22 06:26:59	announced	2024-10-22: Updated project metadata.

Publication List

Bergonzini C, Gregori A, Hagens TMS, van der Noord VE, van de Water B, Zweemer AJM, Coban B, Capula M, Mantini G, Botto A, Finamore F, Garajova I, McDonnell LA, Schmidt T, Giovannetti E, Danen EHJ, ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells. J Exp Clin Cancer Res, 43(1):4(2024) [pubmed]
10.1186/s13046-023-02879-8;
10.6019/PXD040930;

Bergonzini C, Gregori A, Hagens TMS, van der Noord VE, van de Water B, Zweemer AJM, Coban B, Capula M, Mantini G, Botto A, Finamore F, Garajova I, McDonnell LA, Schmidt T, Giovannetti E, Danen EHJ, ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells. J Exp Clin Cancer Res, 43(1):4(2024) [pubmed]

10.1186/s13046-023-02879-8;

10.6019/PXD040930;

Keyword List

submitter keyword: Human, PDAC cell models, Pancreas, LC-MS/MS

submitter keyword: Human, PDAC cell models, Pancreas, LC-MS/MS

Contact List

Elisa Giovannetti
contact affiliation	Cancer Pharmacology Lab, Fondazione Pisana per la Scienza, San Giuliano, Pisa, Italy
contact email	e.giovannetti@vumc.nl
lab head
Francesco Finamore
contact affiliation	Fondazione Pisana per la Scienza ONLUS
contact email	f.finamore@fpscience.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD040930
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD040930

PRIDE project URI

Repository Record List

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