PXD040579-1

PXD040579 is an original dataset announced via ProteomeXchange.

Title	Evidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145
Description	This work was carried out to elucidate the proteins that are regulated by the two-component system CutRS in Streptomyces coelicolor M145 and how this response changes in the presence of glucose. A comparison of the whole cell proteomes of Streptomyces coelicolor M145 WT and Streptomyces coelicolor M145 ∆cutRS on both DNA (no glucose) and DNAD (with glucose) was made.
HostingRepository	PRIDE
AnnounceDate	2023-06-16
AnnouncementXML	Submission_2023-06-16_10:16:45.765.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	GerhardSaalbach
SpeciesList	scientific name: Streptomyces coelicolor A3(2); NCBI TaxID: 100226;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-03 07:56:08	ID requested
⏵ 1	2023-06-16 10:16:46	announced
2	2024-10-22 05:48:28	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: antibiotics,Streptomyces, two-component system, protein secretion, actinorhodin, secretion stress

MattHutchings
contact affiliation	Department Molecular Microbiology John Innes Centre Norwich, UK
contact email	matt.hutchings@jic.ac.uk
lab head
GerhardSaalbach
contact affiliation	Biological Chemistry
contact email	gerhard.saalbach@jic.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD040579

PRIDE project URI

• PRIDE
  1. PXD040579
     1. Label: PRIDE project
     2. Name: Evidence of a role for CutRS and actinorhodin in the secretion stress response in Streptomyces coelicolor M145