PXD040392 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis. |
Description | Project aim was to identify protein-protein interactions of the post-translationally modified form of alpha-synuclein. In situ proximity labeling (BAR) was used to enrich for protein-protein interactions. We performed BAR on wild-type and alpha-synuclein knockout olfactory bulb tissues. We include negative capture conditions, where the primary antibody was omitted. |
HostingRepository | PRIDE |
AnnounceDate | 2023-03-27 |
AnnouncementXML | Submission_2023-03-27_09:18:17.386.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | BryanKillinger |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-02-24 06:19:38 | ID requested | |
⏵ 1 | 2023-03-27 09:18:18 | announced | |
2 | 2023-11-14 08:44:29 | announced | 2023-11-14: Updated project metadata. |
Publication List
Killinger BA, Mercado G, Choi S, Tittle T, Chu Y, Brundin P, Kordower JH, Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis. NPJ Parkinsons Dis, 9(1):43(2023) [pubmed] |
Keyword List
submitter keyword: Proteomics |
neurodegeneration |
vesicles |
protein aggregation. |
Contact List
Bryan AndrewKillinger |
contact affiliation | Assisstant professor. Graduate College. Rush University Medical Center. |
contact email | bryan_killinger@rush.edu |
lab head | |
BryanKillinger |
contact affiliation | Rush University Medical Center |
contact email | bryan_killinger@rush.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD040392 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD040392
- Label: PRIDE project
- Name: Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.