PXD040371-2

PXD040371 is an original dataset announced via ProteomeXchange.

Title	Autophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma
Description	As a first-line drug for treating advanced hepatocellular carcinoma, the resistance to sorafenib has always attracted attention. However, most attention has been focused on a series of mechanisms related to drug resistance caused after sorafenib treatment. In this study, we used proteomic techniques to explore the potential mechanisms by which pre-treatment factors affect sorafenib resistance.
HostingRepository	iProX
AnnounceDate	2023-02-24
AnnouncementXML	Submission_2023-08-14_00:30:42.784.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shuang Weng
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-23 19:24:06	ID requested
1	2023-02-23 19:24:12	announced
⏵ 2	2023-08-14 00:30:43	announced	2023-08-14: Update publication information.

Zheng R, Weng S, Xu J, Li Z, Wang Y, Aizimuaji Z, Ma S, Zheng L, Li H, Ying W, Rong W, Xiao T, Autophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma. Comput Struct Biotechnol J, 21():3564-3574(2023) [pubmed]

submitter keyword: Sorafenib Resistance, Autophagy, Biotransformation, Proteomics

Wantao Ying
contact affiliation	State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing Proteome Research Center, Beijing Institute of Lifeomics; College of Life Science and Bioengineering, Beijing University of Technology
contact email	yingwantao@nspsb.org.cn
lab head
Shuang Weng
contact affiliation	National Center for proteins science (Beinjing); Beijing Proteome Research Center; Institute of Lifeomics
contact email	wengshuanglyf@163.com
dataset submitter

iProX dataset URI