PXD040311 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SECRETORY PROTEOMIC RESPONSES OF ENDOMETRIAL EPITHELIAL CELLS TO TROPHOBLAST DERIVED EXTRACELLULAR VESICLES |
| Description | Synchronized cross talk between embryo and endometrium during pre-implantation period is critical for establishment of pregnancy. Extracellular vesicels(EVs) of both embryo and endometrial origin are known to be integral in regulating embryo maternal communication during this time. However, exact molecular signalling pathways or factors that regulate the embryo endometrial communication during pre-conception period remains elusive. Here in this study extracellular vesicles from trophoblast cells were shown to modulate endometrial epithelial cell secretome in favour of embryo implantation and embryo development. |
| HostingRepository | PRIDE |
| AnnounceDate | 2023-10-24 |
| AnnouncementXML | Submission_2023-10-24_12:04:17.009.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | SUBHASHINI MUHANDIRAMMUHANDIRAM RALALAGE |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-02-21 02:46:10 | ID requested | |
| ⏵ 1 | 2023-10-24 12:04:18 | announced | |
| 2 | 2023-11-14 09:08:35 | announced | 2023-11-14: Updated project metadata. |
| 3 | 2024-10-22 06:09:30 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Muhandiram S, Dissanayake K, Orro T, Godakumara K, Kodithuwakku S, Fazeli A, Secretory Proteomic Responses of Endometrial Epithelial Cells to Trophoblast-Derived Extracellular Vesicles. Int J Mol Sci, 24(15):(2023) [pubmed] |
Keyword List
| submitter keyword: Embryo, Extracellular Vesicles, LC-MS, Endometrium, Epithelial cells, Trophoblast cells, Secretome, Proteomics |
Contact List
| AlirezaFazeli |
|---|
| contact affiliation | Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006, Tartu, Estonia |
| contact email | fazeli@emu.ee |
| lab head | |
| SUBHASHINI MUHANDIRAMMUHANDIRAM RALALAGE |
|---|
| contact affiliation | Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences |
| contact email | soomuhandiram2@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD040311 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD040311
- Label: PRIDE project
- Name: SECRETORY PROTEOMIC RESPONSES OF ENDOMETRIAL EPITHELIAL CELLS TO TROPHOBLAST DERIVED EXTRACELLULAR VESICLES
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