PXD040294-2

PXD040294 is an original dataset announced via ProteomeXchange.

Title	Proteome and phosphoproteome analysis of skeletal muscle from Glut4 mutant mouse
Description	This study aimed to investigate the effects of glucose restriction (GR) on energy metabolism and muscle fiber type in skeletal muscle. To achieve this goal, we created a mouse model of innate glucose limitation by mutating the major glucose transporter 4 (Glut4) in skeletal muscle. We performed proteomic and phosphoproteomic analyzes of gastrocnemius samples from 12-week-old male Glut4m mice, with or without low-intensity treadmill training.
HostingRepository	iProX
AnnounceDate	2023-02-21
AnnouncementXML	Submission_2024-02-22_18:26:59.537.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kaiyi Zhang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-20 18:17:16	ID requested
1	2023-11-15 19:40:14	announced
⏵ 2	2024-02-22 18:27:00	announced	2024-02-23: Update information.

Zhang K, Xie N, Ye H, Miao J, Xia B, Yang Y, Peng H, Xu S, Wu T, Tao C, Ruan J, Wang Y, Yang S, Glucose restriction enhances oxidative fiber formation: A multi-omic signal network involving AMPK and CaMK2. iScience, 27(1):108590(2024) [pubmed]

submitter keyword: mouse model, glucose restriction, glucose transporter 4, muscle fibers

Shulin Yang
contact affiliation	Institute of Animal Science, Chinese Academy of Agricultural Sicences
contact email	yangshulin@caas.cn
lab head
Kaiyi Zhang
contact affiliation	Institute of Animal Science, Chinese Academy of Agricultural Sciences
contact email	kaiyi.zhang1016@outlook.com
dataset submitter

iProX dataset URI