PXD040229-1

PXD040229 is an original dataset announced via ProteomeXchange.

Title	MiRNA 3’ ends shorten during adolescent brain maturation
Description	MicroRNA (miRNA) dysregulation is well-documented in psychiatric disease, but miRNA dynamics during adolescent and early adult brain maturation, when symptoms first appear for many of these diseases, remain poorly understood. Here, we use RNA sequencing to examine miRNAs and their mRNA targets in cortex and hippocampus from early, mid-, and late adolescent and adult mice. We also use Quantitative Proteomics by tandem mass tag mass spectrometry (TMT-MS) to examine protein dynamics in cortex from the same subjects.
HostingRepository	PRIDE
AnnounceDate	2023-02-17
AnnouncementXML	Submission_2023-02-17_07:40:45.038.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AshutoshMishra
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF; Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-17 02:33:20	ID requested
⏵ 1	2023-02-17 07:40:45	announced

Dataset with its publication pending

submitter keyword: miRNA, Cortex, Proteomics, RNA-Seq

Stanislav S.Zakharenko
contact affiliation	Division of Neural Circuits and Behavior, Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis TN 38105, USA
contact email	stanislav.zakharenko@stjude.org
lab head
AshutoshMishra
contact affiliation	St. Jude Children's Research Hospital
contact email	ashutosh.mishra@stjude.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD040229

PRIDE project URI

• PRIDE
  1. PXD040229
     1. Label: PRIDE project
     2. Name: MiRNA 3’ ends shorten during adolescent brain maturation