PXD040198-2

PXD040198 is an original dataset announced via ProteomeXchange.

Title	Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function
Description	Dysregulated mitochondrial function is a common feature in several malignancies, includingpancreatic cancer. Although mitochondria have their own genome, most mitochondrial proteins are nuclear-encoded and imported by a multi-subunit translocase of the outer mitochondrial membrane (TOMM). TOMM22 is the central receptor of the TOMM complex and plays a role incomplex assembly. We aim to understand the pathobiological roles of TOMM subunits in PC.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:47:27.720.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	SANTANU DASGUPTA
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-16 14:22:20	ID requested
1	2023-10-25 09:32:43	announced
⏵ 2	2023-11-14 07:47:28	announced	2023-11-14: Updated project metadata.
3	2024-10-22 06:13:20	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: TOMM22,Pancreatic cancer, respiratory complex, mitochondria, protein import, OXPHOS., translocases

Santanu Dasgupta
contact affiliation	Assistant Professor Department of Pathology University of South Alabama Mobile, Alabama United States
contact email	dasgupta@southalabama.edu
lab head
SANTANU DASGUPTA
contact affiliation	UNIVERSITY OF SOUTH ALABAMA
contact email	dasgupta@southalabama.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD040198
     1. Label: PRIDE project
     2. Name: Mitochondrial translocase TOMM22 is overexpressed in pancreatic cancer and promotes aggressive growth by modulating mitochondrial protein import and function