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PXD040018-4

PXD040018 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInteractome of activated BAX in Senescent Cells.
DescriptionWe aimed to identify the interactome of activated BAX in the mitochondria of senescent cells. Our goal was to understand which factors can directly mediate the formation of BAX pores in senescent cells.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:00:09.269.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKarolina Szczepanowska
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-02-10 04:47:48ID requested
12023-08-13 05:51:25announced
22023-10-27 01:37:53announced2023-10-27: Updated project metadata.
32023-11-14 09:13:40announced2023-11-14: Updated project metadata.
42024-10-22 06:00:10announced2024-10-22: Updated project metadata.
Publication List
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF, Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature, 622(7983):627-636(2023) [pubmed]
10.1038/s41586-023-06621-4;
Keyword List
submitter keyword: mtDNA,cellular senescence, bax, mitochondria
Contact List
Karolina Szczepanowska
contact affiliationIMol Polish Academy of Sciences, Warsaw, Poland
contact emailk.szczepanowska@imol.institute
lab head
Karolina Szczepanowska
contact affiliationInstitute of Mitochondrial Disease and Ageing, Medical Faculty, University of Cologne
contact emailkarolina.szczepanowska.phd@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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