PXD039433-2

PXD039433 is an original dataset announced via ProteomeXchange.

Title	Non-labelled proteomics expression analysis of PC-3 cells treated with transferrin conjugated gold nanoparticles
Description	Nanoparticles-based therapeutics are being clinically translated for treating cancer. Meanwhile nanoparticles are increasingly being identified as impacting cell regulation and protein expression. Here, we sought to understand how a model of a relatively inert nanoparticle without any therapeutic agent itself interact with the cells and what are the key biological mechanisms.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:07:04.524.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sonia Theresa Sebastian
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-13 14:26:52	ID requested
1	2023-10-24 11:01:06	announced
⏵ 2	2023-11-14 09:07:06	announced	2023-11-14: Updated project metadata.
3	2024-10-22 06:08:23	announced	2024-10-22: Updated project metadata.

Sebastian S, Hoffmann MK, Howard D, Young C, Washington J, Unterweger H, Alexiou C, Turnbull T, D'Andrea R, Hoffmann P, Kempson I, Kinetic Effects of Transferrin-Conjugated Gold Nanoparticles on the Antioxidant Glutathione-Thioredoxin Pathway. Antioxidants (Basel), 12(8):(2023) [pubmed]

submitter keyword: antioxidant, proteomics, TEM, reactive oxygen species, nanoparticle, glutathione-thioredoxin

Associate Professor Ivan Kempson
contact affiliation	University of South Australia
contact email	ivan.kempson@unisa.edu.au
lab head
Sonia Theresa Sebastian
contact affiliation	University of South Australia
contact email	soniasebi@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD039433

PRIDE project URI

• PRIDE
  1. PXD039433
     1. Label: PRIDE project
     2. Name: Non-labelled proteomics expression analysis of PC-3 cells treated with transferrin conjugated gold nanoparticles