PXD039338 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome profiling of plasma from patients with lung adenocarcinoma and malignant melanoma. |
Description | Here, we have reported the plasma proteomes of 6 malignant melanoma (MM) and 6 lung adenocarcinoma (LUAD) patients, generated using HiRIEF pre-fractionation and tandem mass tags (TMT)-based peptide quantification. We have detected traditional plasma marker proteins, as well as many LUAD and MM related proteins in the cancer plasma. Our advanced proteomics workflow exhibits high proteome coverage for both plasma and plasma derived extracellular vesicles (pEVs), providing the ability to detect potential disease-specific markers in pEVs enriched from clinical plasma samples. |
HostingRepository | PRIDE |
AnnounceDate | 2024-08-15 |
AnnouncementXML | Submission_2024-08-15_03:01:50.285.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Nidhi Sharma |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-01-09 07:37:06 | ID requested | |
⏵ 1 | 2024-08-15 03:01:50 | announced | |
2 | 2024-10-22 06:55:14 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
submitter keyword: cancer, lung adenocarcinoma, proteomics, mass spectrometry, liquid biopsy, HiRIEF,plasma, malignant melanoma |
Contact List
Dr Janne Lehtiƶ |
contact affiliation | Department of Oncology Pathology, Karolinska Institute, Solna, Sweden |
contact email | janne.lehtio@ki.se |
lab head | |
Nidhi Sharma |
contact affiliation | Karolinska Institute |
contact email | nidhi.sharma@ki.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD039338
- Label: PRIDE project
- Name: Proteome profiling of plasma from patients with lung adenocarcinoma and malignant melanoma.