PXD039260-1
PXD039260 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Bispecific antigen therapy plasma proteome |
| Description | Bispecific-antibody therapy (BAT), the next strategy of immunotherapy for tumor patients, has showed the enhanced antitumor benefits than the monotherapy. Yet, few effective biomarkers were developed to monitor the response. Here, we investigated the first BAT longitudinal plasma proteome profiling including 86 longitudinal samples from 22 tumor patients who received anti-PD1 and anti-CTLA4 BAT therapy and 24 healthy control samples, which might be beneficial to explore the biomarker for BAT. |
| HostingRepository | iProX |
| AnnounceDate | 2024-02-20 |
| AnnouncementXML | Submission_2024-08-05_20:14:43.598.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jiacheng Lyu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-01-04 20:20:20 | ID requested | |
| ⏵ 1 | 2024-08-05 20:14:44 | announced | |
| 2 | 2025-06-12 21:21:54 | announced | 2025-06-13: Add Publication. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: immunotherapy, bispecific antigen therapy, plasma proteome, biomarker |
Contact List
| Chen Ding | |
|---|---|
| contact affiliation | Fudan University |
| contact email | crickding@163.com |
| lab head | |
| Jiacheng Lyu | |
| contact affiliation | Fudan University |
| contact email | jydcz1028@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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