PXD038693 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The central nervous system’s proteogenomic and spatial imprint upon systemic viral infection, like SARS-CoV-2 |
Description | During severe systemic infections with and without sepsis neurological changes are common and range from sickness behavior to septic associated encephalopathy. Encephalopathy is due to a system-wide inflammatory response leading to an often fatal increase in the permeability of the blood-brain barrier. To elucidate the cytotoxic impact and brain-specific host response during coronavirus disease 2019 (COVID-19), we profiled the olfactory mucosa, olfactory bulb, brainstem and cerebellum from deceased COVID-19 patients who underwent rapid autopsy. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-06 |
AnnouncementXML | Submission_2023-11-06_14:42:40.570.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | MichaelMülleder |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-12-08 16:23:11 | ID requested | |
⏵ 1 | 2023-11-06 14:42:40 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19 |
submitter keyword: COVID-19, encephalopathy |
Contact List
HelenaRadbruch |
contact affiliation | Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neuropathology, Charitéplatz 1, 10117 Berlin, Germany |
contact email | helena.radbruch@charite.de |
lab head | |
MichaelMülleder |
contact affiliation | Core Facility -High-Throughput Mass Spectrometry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany |
contact email | michael.muelleder@charite.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD038693 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD038693
- Label: PRIDE project
- Name: The central nervous system’s proteogenomic and spatial imprint upon systemic viral infection, like SARS-CoV-2