PXD038615-2

PXD038615 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	LINE-1 ORF2p Structure. BS3 crosslinks
Description	ORF2p was cross-linked using BS3 in order to gather experimental data that could help elucidate its structure.
HostingRepository	PRIDE
AnnounceDate	2024-03-14
AnnouncementXML	Submission_2024-03-14_03:20:30.395.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Luciano Di Stefano
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	methylthiolated residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-07 06:01:03	ID requested
1	2023-12-12 06:47:51	announced
⏵ 2	2024-03-14 03:20:31	announced	2024-03-14: Updated project metadata.

Publication List

10.1038/s41586-023-06947-z;
Baldwin ET, van Eeuwen T, Hoyos D, Zalevsky A, Tchesnokov EP, S, á, nchez R, Miller BD, Di Stefano LH, Ruiz FX, Hancock M, I, ş, ik E, Mendez-Dorantes C, Walpole T, Nichols C, Wan P, Riento K, Halls-Kass R, Augustin M, Lammens A, Jestel A, Upla P, Xibinaku K, Congreve S, Hennink M, Rogala KB, Schneider AM, Fairman JE, Christensen SM, Desrosiers B, Bisacchi GS, Saunders OL, Hafeez N, Miao W, Kapeller R, Zaller DM, Sali A, Weichenrieder O, Burns KH, G, ö, tte M, Rout MP, Arnold E, Greenbaum BD, Romero DL, LaCava J, Taylor MS, Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626(7997):194-206(2024) [pubmed]

10.1038/s41586-023-06947-z;

Baldwin ET, van Eeuwen T, Hoyos D, Zalevsky A, Tchesnokov EP, S, á, nchez R, Miller BD, Di Stefano LH, Ruiz FX, Hancock M, I, ş, ik E, Mendez-Dorantes C, Walpole T, Nichols C, Wan P, Riento K, Halls-Kass R, Augustin M, Lammens A, Jestel A, Upla P, Xibinaku K, Congreve S, Hennink M, Rogala KB, Schneider AM, Fairman JE, Christensen SM, Desrosiers B, Bisacchi GS, Saunders OL, Hafeez N, Miao W, Kapeller R, Zaller DM, Sali A, Weichenrieder O, Burns KH, G, ö, tte M, Rout MP, Arnold E, Greenbaum BD, Romero DL, LaCava J, Taylor MS, Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626(7997):194-206(2024) [pubmed]

Keyword List

submitter keyword: ORF2 ORF2p LINE-1 BS3 Structural Proteomics

submitter keyword: ORF2 ORF2p LINE-1 BS3 Structural Proteomics

Contact List

John LaCava
contact affiliation	ERIBA - UMCG (lab head)
contact email	j.p.lacava@rug.nl
lab head
Luciano Di Stefano
contact affiliation	ERIBA - UMCG
contact email	luciano.lhd@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD038615
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD038615

PRIDE project URI

Repository Record List

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