PXD038562-1

PXD038562 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Endoplasmic Reticulum (ER) Kinase PERK Interacts with the Oxidoreductase ERO1 to Mediate Metabolic Adaptation to ER Stress
Description	Our study has shown that during the initiation of ER-stress the oxidoreductase ERO1⍺ covalently interacts with PERK at the MERCs domain. The complex promotes oxidization of MERC proteins and controls mitochondrial dynamics to adapt to new energy needs.
HostingRepository	jPOST
AnnounceDate	2022-12-06
AnnouncementXML	Submission_2022-12-05_13:50:36.080.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ba@160592
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-05 13:50:33	ID requested
⏵ 1	2022-12-05 13:50:36	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Mitochondria, Endoplasmic Reticulum (ER), Mitochondria-Associated Membranes, Bioenergetics, ER Stress, PERK, Oxidoreductase

submitter keyword: Mitochondria, Endoplasmic Reticulum (ER), Mitochondria-Associated Membranes, Bioenergetics, ER Stress, PERK, Oxidoreductase

Contact List

Arthur Bassot (Thomas Simmen Lab)
lab head
Ba@160592
contact affiliation	University of Alberta (T. Simmen Lab)
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001942/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001942/