PXD038310-2

PXD038310 is an original dataset announced via ProteomeXchange.

Title	Coalescence of endoplasmic reticulum fragments form a new quality-control compartment in adipocytes
Description	Using a combination of state-of-the-art (ultra-) imaging, biochemical and biophysical techniques, this study not only uncover a new cellular quality-control compartment, but demonstrate a profound cellular adaptation capability and plasticity in dealing with misfolded proteins or protein aggregates in the ER.
HostingRepository	PRIDE
AnnounceDate	2024-10-03
AnnouncementXML	Submission_2024-10-03_05:48:15.091.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaoqiong Wei
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-11-23 04:25:14	ID requested
1	2023-04-25 11:30:39	announced
⏵ 2	2024-10-03 05:48:16	announced	2024-10-03: Updated project metadata.

Wu SA, Shen C, Wei X, Zhang X, Wang S, Chen X, Torres M, Lu Y, Lin LL, Wang HH, Hunter AH, Fang D, Sun S, Ivanova MI, Lin Y, Qi L, The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes. Nat Commun, 14(1):3132(2023) [pubmed]

10.1038/s41467-023-38690-4;

submitter keyword: autophagy, lipoprotein lipase, tryptophan loop,SEL1L-HRD1 ERAD, CERFs, BiP, ER-phagy, protein aggregation, phase separation, soluble-to-insoluble phase transition

Ling Qi
contact affiliation	Department of Molecular & Integrative Physiology,University of Michigan Medical School, 5325 Brehm Tower, 1000 Wall St., Ann Arbor, MI, 48105
contact email	lingq@umich.edu
lab head
Xiaoqiong Wei
contact affiliation	University of Michigan
contact email	weixi@umich.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD038310

PRIDE project URI

• PRIDE
  1. PXD038310
     1. Label: PRIDE project
     2. Name: Coalescence of endoplasmic reticulum fragments form a new quality-control compartment in adipocytes