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PXD038063-2

PXD038063 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass spectrometry analysis of proteins interacting with STING mutants
DescriptionTo investigate proteins interacting with STING mutants, HEK 293T cells were co-transfected with three STING mutant expression plasmids (human STING WT, STING delCTT (aa343-379 deletion), STING del6 (aa325-379 deletion) in a pcDNA3.1+ backbone) and either pcDNA-cGAS expression plasmid or control empty pcDNA plasmid. Lysed cells were then immunoprecipitated using sheep anti-STING or control sheep anti-IgG antibodies and protein G magnetic Dynabeads.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:31:08.150.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQi Wu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-11-09 10:31:48ID requested
12024-02-19 06:13:17announced
22024-10-22 06:31:08announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: STING mutants, HEK 293T, STING-interacting proteins, LC-MS/MS
Contact List
Søren Riis Paludan
contact affiliationDepartment of Biomedicine, Aarhus University
contact emailsrp@biomed.au.dk
lab head
Qi Wu
contact affiliationDepartment of Biomedicine, Aarhus University
contact emailqi.wu@biomed.au.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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