PXD037942 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Thermal proteome profiling in Cryptosporidium parvum |
| Description | Cryptosporidium lacks tools that can identify the targets of emerging compounds that have been developed against this parasite. Thermal proteomic profiling is an unbiased approach that fulfils this unmet need by detecting changes in the thermal stability of target proteins upon the binding of their inhibitor. This technique has been successfully used in other protozoan parasites and here we report the validation and first use of thermal proteome profiling in Cryptosporidium. |
| HostingRepository | PRIDE |
| AnnounceDate | 2023-06-13 |
| AnnouncementXML | Submission_2023-06-13_10:01:51.695.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | VictorianoCorpas-Lopez |
| SpeciesList | scientific name: Cryptosporidium parvum Iowa II; NCBI TaxID: 353152; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2022-11-03 05:17:08 | ID requested | |
| ⏵ 1 | 2023-06-13 10:01:52 | announced | |
| 2 | 2024-10-22 05:48:01 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: drug target, lysyl-tRNA synthetase, Cryptosporodium parvum,thermal proteome profiling |
Contact List
| MattiePawlowic |
|---|
| contact affiliation | WCAIR, School of Life Sciences, University of Dundee, UK |
| contact email | mcpawlowic@dundee.ac.uk |
| lab head | |
| VictorianoCorpas-Lopez |
|---|
| contact affiliation | University of Dundee |
| contact email | vcorpaslopez@dundee.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037942 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037942
- Label: PRIDE project
- Name: Thermal proteome profiling in Cryptosporidium parvum
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