PXD037844-1

PXD037844 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Human Beta Defensin-2-mediated protection of human skin barrier in vitro; a mechanistic evaluation
Description	I this project we performed global proteomic and secretomic analyses, following HBD2 stimulation, with or without V8-mediated damage, demonstrating minimal impact of the peptide alone on undamaged cells and showing that HBD2 did not induce expression of known antiproteases, but rather may function by modulating expression of extracellular matrix proteins.
HostingRepository	PRIDE
AnnounceDate	2023-02-09
AnnouncementXML	Submission_2023-02-09_07:03:37.026.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	JimiWills
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-31 09:04:54	ID requested
⏵ 1	2023-02-09 07:03:37	announced
2	2023-11-14 08:58:35	announced	2023-11-14: Updated project metadata.

Publication List

Keyword List

submitter keyword: Defensins
Antimicrobial Host Defence Peptide
Atopic Dermatitis
Staphylococcus aureus

submitter keyword: Defensins

Antimicrobial Host Defence Peptide

Atopic Dermatitis

Staphylococcus aureus

Contact List

Donald J.Davidson
contact affiliation	University of Edinburgh Centre for Inflammation Research, Queen’s Medical Research Institute, University of Edinburgh, Scotland, UK
contact email	Donald.Davidson@ed.ac.uk
lab head
JimiWills
contact affiliation	Firefinch Software Ltd formerly Univeristy of Edinburgh
contact email	jimi@firefinch.io
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD037844
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD037844

PRIDE project URI

Repository Record List

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