PXD037782-1

PXD037782 is an original dataset announced via ProteomeXchange.

Title	Characterizing the origin of blood plasma proteins from organ tissues in rainbow trout (Oncorhynchus mykiss) using a comparative non-targeted proteomics approach
Description	Protein expression patterns adapt to various cues to meet the needs of an organism. The dynamicity of an organism’s proteome can therefore reveal information about an organism’s health. Proteome databases contain limited information regarding organisms outside of medicinal biology. The Uniprot human and mouse proteomes are extensively reviewed and ~50% of both proteomes include tissue specificity, while >99% of the rainbow trout proteome lacks tissue specificity. This study aimed to expand knowledge on the rainbow trout proteome with a focus on understanding the origin of blood plasma proteins. Blood, brain, heart, liver, kidney, and gills were collected from adult rainbow trout, plasma and tissue proteins were analyzed using liquid chromatography tandem mass spectrometry. Over 10,000 proteins were identified across all groups. Our data indicated that the majority of the plasma proteome is shared among multiple tissue types, though 4-7% of the plasma proteome is uniquely originated from each tissue (gill > heart > liver > kidney > brain).
HostingRepository	PanoramaPublic
AnnounceDate	2023-03-31
AnnouncementXML	Submission_2023-03-31_09:30:32.563.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Denina Simmons
SpeciesList	scientific name: Oncorhynchus mykiss; NCBI TaxID: 8022;
ModificationList	Phospho; Gln->pyro-Glu; Carbamyl; Carbamidomethyl; Oxidation
Instrument	6545 Q-TOF LC/MS; 1200 series LC/MSD SL

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-27 18:31:38	ID requested
⏵ 1	2023-03-31 09:30:33	announced

Tannouri N, Simmons DBD, Characterizing the origin of blood plasma proteins from organ tissues in rainbow trout (Oncorhynchus mykiss) using a comparative non-targeted proteomics approach. Comp Biochem Physiol Part D Genomics Proteomics, 46():101070(2023) [pubmed]

submitter keyword: proteomics, blood plasma, rainbow trout, fish, tissue or origin

Denina Simmons
contact affiliation	Ontario Tech University, Oshawa ON, Canada
contact email	denina.simmons@ontariotechu.ca
lab head
Denina Simmons
contact affiliation	Ontario Tech University, Oshawa ON, Canada
contact email	denina.simmons@ontariotechu.ca
dataset submitter

Panorama Public dataset URI