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PXD037648-1

PXD037648 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation
DescriptionSENP1 deSUMOylates RIPK1 in TNF-R1 signaling complex (TNF-RSC), keeping RIPK1 in check. Loss of SENP1 leads to SUMOylation of RIPK1, which re-orchestrates TNF-RSC and modulates the ubiquitination patterns and activity of RIPK1.
HostingRepositoryiProX
AnnounceDate2022-10-24
AnnouncementXMLSubmission_2022-10-24_00:34:56.150.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBing Shan
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-10-24 00:34:37ID requested
⏵ 12022-10-24 00:34:56announced
22022-12-07 23:16:18announced2022-12-08: Update publication information.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: SENP1
Contact List
Daichao Xu
contact affiliationShanghai institute of Organic Chemistry,CAS
contact emailxudaichao@sioc.ac.cn
lab head
Bing Shan
contact affiliationShanghai institute of Organic Chemistry,CAS
contact emailshanbing@sioc.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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