PXD037505-1

PXD037505 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Urinary proteomics anlaysis of Type 2 Diabetic Nephropathy
Description	Type 2 Diabetic Nephropathy (T2DN), in the setting of type 2 diabetes, is the world占쎌뀼 leading cause of chronic kidney disease and end-stage kidney disease (ESKD). The increasing prevalence and heterogeneous phenotype of T2DN complicate the approach to treating patients. While kidney biopsy is the gold standard for exclusion of non-DN diagnoses and confirming diagnosis of DN, it is imperfect in predicting progression to ESKD. Artificial intelligence (AI) has the potential to improve classification of T2DN, predict progression risk, and via integration with urinary proteomic profiles identify novel urinary biomarkers, taken together augmenting and going beyond current pathology practice.
HostingRepository	PRIDE
AnnounceDate	2025-07-28
AnnouncementXML	Submission_2025-07-28_06:19:00.909.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dohyun Han
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-17 01:51:09	ID requested
⏵ 1	2025-07-28 06:19:01	announced

Publication List

10.1016/j.ekir.2025.04.061;
Yun D, Bae S, Gao Y, Lopez L, Han D, Nicora CD, Kim TY, Moon KC, Kim DK, Fillmore TL, Kim YS, Rosenberg AZ, Wang W, Sarder P, Qian WJ, Afkarian M, Han SS, Complement Proteins Identify Rapidly Progressive Diabetic Kidney Disease. Kidney Int Rep, 10(7):2296-2310(2025) [pubmed]

10.1016/j.ekir.2025.04.061;

Yun D, Bae S, Gao Y, Lopez L, Han D, Nicora CD, Kim TY, Moon KC, Kim DK, Fillmore TL, Kim YS, Rosenberg AZ, Wang W, Sarder P, Qian WJ, Afkarian M, Han SS, Complement Proteins Identify Rapidly Progressive Diabetic Kidney Disease. Kidney Int Rep, 10(7):2296-2310(2025) [pubmed]

Keyword List

submitter keyword: Urine, proteomics, T2D

submitter keyword: Urine, proteomics, T2D

Contact List

Dohyun Han
contact affiliation	Proteomics core facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
lab head
Dohyun Han
contact affiliation	Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD037505
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD037505

PRIDE project URI

Repository Record List

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