PXD037232 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LFQ proteomics analysis of M. smegmatis treated with CymA and ecumicin (Part 1). |
| Description | To assess the impact of the bactericidal compounds CymA and ecumicin on the mycobacterial proteome and to monitor proteome remodeling by the AAA+ ClpC1 protease machinery, we performed a LFQ proteomics analysis treating the cells at sub-bactericidal compound concentration. We identified new players of the mycobacterial ClpC1 stress response (ClpC2 and ClpC3), as novel bacterial antibiotic resistance mechanism. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_05:47:04.847.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | David Hoi |
| SpeciesList | scientific name: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155); NCBI TaxID: 246196; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2022-10-10 07:12:34 | ID requested | |
| 1 | 2023-06-07 02:52:28 | announced | |
| 2 | 2023-11-14 08:58:20 | announced | 2023-11-14: Updated project metadata. |
| ⏵ 3 | 2024-10-22 05:47:05 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
| submitter keyword: tuberculosis,tpd,protein degradation |
Contact List
| Markus Hartl |
|---|
| contact affiliation | Max Perutz Labs, Vienna, Austria |
| contact email | markus.hartl@univie.ac.at |
| lab head | |
| David Hoi |
|---|
| contact affiliation | IMP |
| contact email | david.hoi@imp.ac.at |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD037232 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037232
- Label: PRIDE project
- Name: LFQ proteomics analysis of M. smegmatis treated with CymA and ecumicin (Part 1).
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