PXD036891-1

PXD036891 is an original dataset announced via ProteomeXchange.

Title	A proteomic signature for human papillomavirus-associated oropharyngeal squamous cell carcinoma predicts patients at high risk of recurrence
Description	The incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is increasing and effective treatment for targeting the subset of patients at high risk for recurrence remains a significant clinical challenge. In this study, pre-treatment tumour biopsies were used for proteomic analysis by data-independent acquisition mass spectrometry (DIA-MS) to identify protein and peptide biomarker signatures able to stratify patients at low, intermediate, or high-risk of recurrence. For further details, refer to the publication that accompanies this data deposition.
HostingRepository	PRIDE
AnnounceDate	2025-02-25
AnnouncementXML	Submission_2025-02-25_04:57:11.235.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Peter Hains
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 6600

Revision	Datetime	Status	ChangeLog Entry
0	2022-09-21 02:02:48	ID requested
⏵ 1	2025-02-25 04:57:11	announced

Dataset with its publication pending

submitter keyword: HPV,Human papillomavirus, Data-independent acquisition, DIA, Predictive biomarkers, OPSCC, Oropharyngeal squamous cell carcinoma, Proteomics

Phil Robinson
contact affiliation	ProCan, Children’s Medical Research Institute, The University of Sydney, Westmead, NSW, Australia
contact email	probinson@cmri.org.au
lab head
Peter Hains
contact affiliation	Children's Medical Research Institute
contact email	phains@cmri.org.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD036891

PRIDE project URI

• PRIDE
  1. PXD036891
     1. Label: PRIDE project
     2. Name: A proteomic signature for human papillomavirus-associated oropharyngeal squamous cell carcinoma predicts patients at high risk of recurrence