PXD036853-1
PXD036853 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Global Analysis of Lysine Acetylation in the Brain Cortex of K18-hACE2 Mice Infected with SARS-CoV-2 |
Description | In order to research the relationship between neurological sequelae of COVID-19 and acetylation of brain cortexes, we reported for the first time the acetylome in the brain cortex of the K18-hACE2 infected mouse model, and the difference between the SARS-CoV-2 infection group and the control group, which found the largest amount of acetylated proteins in the brain cortex of the mouse to date, greatly expanding the existing database of acetylome. Besides, it would also lay a foundation for the subsequent research on the pathogenesis and treatment of COVID-19 patients. |
HostingRepository | iProX |
AnnounceDate | 2022-09-20 |
AnnouncementXML | Submission_2024-03-20_00:11:45.153.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Qiaochu Wang |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | acetylated residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-09-20 00:18:20 | ID requested | |
⏵ 1 | 2024-03-20 00:11:46 | announced |
Publication List
Wang Q, Peng W, Yang Y, Wu Y, Han R, Ding T, Zhang X, Liu J, Liu J, Yang J, Global analysis of lysine acetylation in the brain cortex of K18-hACE2 mice infected with SARS-CoV-2. Proteomics, 23(16):e2300096(2023) [pubmed] |
Keyword List
submitter keyword: Brain cortex, Lysine acetylation, K18-hACE2, SARS-CoV-2 |
Contact List
Juntao Yang | |
---|---|
contact affiliation | Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences |
contact email | yangjt@pumc.edu.cn |
lab head | |
Qiaochu Wang | |
contact affiliation | Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences |
contact email | wangqiaochu@ibms.pumc.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |