PXD036388-2

PXD036388 is an original dataset announced via ProteomeXchange.

Title	PTMC_The proteomic profiles of pyridinium-based strategy for lysine-selective protein modification in live cells
Description	A new bioorthogonal lysine-labeling strategy based on cationic-pyridinium activated ester, which renders the modification of peptides and proteins’ lysine residues with ultrafast kinetics and excellent specificity under aqueous solution, and profiled reactive-lysine proteome in vitro and in live cells.
HostingRepository	iProX
AnnounceDate	2023-10-24
AnnouncementXML	Submission_2024-05-20_20:15:08.041.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuhao An
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-30 01:41:42	ID requested
1	2022-12-02 00:11:56	announced
⏵ 2	2024-05-20 20:15:08	announced	2024-05-21: Update information.

Wan C, Yang D, Song C, Liang M, An Y, Lian C, Dai C, Ye Y, Yin F, Wang R, Li Z, A pyridinium-based strategy for lysine-selective protein modification and chemoproteomic profiling in live cells. Chem Sci, 15(14):5340-5348(2024) [pubmed]

submitter keyword: pyridium activated ester, ABPP, reactive-lysine residues, in live cells

Zigang Li
contact affiliation	Pingshan Translational Medicine Center, Shenzhen Bay Laboratory
contact email	lizg@szbl.ac.cn
lab head
Yuhao An
contact affiliation	Pingshan Translational Medicine Center, Shenzhen Bay Laboratory
contact email	anchiyuhao@vip.qq.com
dataset submitter

iProX dataset URI