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PXD036235-1

PXD036235 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleANXA1 promotes tumor immune evasion by binding PARP1 and upregulating the transcription of PD-L1 in the multiple cancers
DescriptionTo search proteins that interact with ANXA1, ANXA1 interactors were coimmunoprecipitated with anti-ANXA1 antibody from MB231 cell extracts, separated on SDS-PAGE and stained with Coomassie blue , and non-immune IgG antibody instead of anti-ANXA1 antibody served as control. All bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of 489 proteins including PARP1 were identified .
HostingRepositoryiProX
AnnounceDate2022-08-23
AnnouncementXMLSubmission_2024-03-20_00:10:44.811.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterShanshan Lu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-22 23:12:55ID requested
12024-03-20 00:10:45announced
Publication List
Keyword List
submitter keyword: ANXA1, PARP1, PD-L1, cancerimmune evasion, cancer
Contact List
Zhiqiang Xiao
contact affiliationResearch Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact emailzqxiao2001@hotmail.com
lab head
Shanshan Lu
contact affiliationResearch Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact emailsusan880102@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI