PXD036188-1

PXD036188 is an original dataset announced via ProteomeXchange.

Title	Thermal proteome profiling of ticagrelor in Staphylococcus aureus
Description	We performed two dimensional thermal proteome profiling (2D-TPP) of ticagrelor to study its impact in Staphylococcus aureus.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-26_07:12:04.092.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	André Mateus
SpeciesList	scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-21 03:55:18	ID requested
⏵ 1	2024-01-26 07:12:05	announced

10.1038/s41564-023-01486-9;

Cacace E, Kim V, Varik V, Knopp M, Tietgen M, Brauer-Nikonow A, Inecik K, Mateus A, Milanese A, M, å, rli MT, Mitosch K, Selkrig J, Brochado AR, Kuipers OP, Kjos M, Zeller G, Savitski MM, G, ö, ttig S, Huber W, Typas A, Systematic analysis of drug combinations against Gram-positive bacteria. Nat Microbiol, 8(11):2196-2212(2023) [pubmed]

submitter keyword: target engagement, ticagrelor, drugs, Staphylococcus aureus,thermal proteome profiling

Athanasios Typas
contact affiliation	European Molecular Biology Laboratory
contact email	typas@embl.de
lab head
André Mateus
contact affiliation	Umeå University
contact email	andre.mateus@umu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD036188

PRIDE project URI

• PRIDE
  1. PXD036188
     1. Label: PRIDE project
     2. Name: Thermal proteome profiling of ticagrelor in Staphylococcus aureus