PXD036161-1

PXD036161 is an original dataset announced via ProteomeXchange.

Title	High-throughput proteomics of the 26 medically most important elapids and vipers from sub-Saharan Africa
Description	Venomous snakes are important parts of the ecosystem, and their behavior and evolution have been shaped by their surrounding environments over the eons. This is reflected in their venoms, which are typically highly adapted for their biological niche, including their diet and defense mechanisms for deterring predators. Sub-Saharan Africa is rich in venomous snake species, of which many are dangerous to humans due to the high toxicity of their venoms and their ability to effectively deliver large amounts of venom into their victims via their bite. In this study, the venoms of 26 of sub-Saharan Africa’s medically most relevant elapid and viper species were subjected to parallelized toxicovenomics analysis. The analysis included venom proteomics and enables a robust comparison of venom profiles between species. Moreover, two new venom proteomes (N. anchietae and E. leucogaster) are presented here for the first time.
HostingRepository	PRIDE
AnnounceDate	2022-10-17
AnnouncementXML	Submission_2022-10-17_06:10:37.324.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	CarolO'Brien
SpeciesList	scientific name: Cerastes cerastes; NCBI TaxID: 8697; scientific name: Hemachatus haemachatus; NCBI TaxID: 8626; scientific name: Dendroaspis viridis; NCBI TaxID: 8621; scientific name: Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps); NCBI TaxID: 8618; scientific name: Naja nivea; NCBI TaxID: 8655; scientific name: Dendroaspis polylepis; NCBI TaxID: 8624; scientific name: Naja katiensis; NCBI TaxID: 409859; scientific name: Naja haje; NCBI TaxID: 8639; scientific name: Echis pyramidum; NCBI TaxID: 8700; scientific name: Naja senegalensis; NCBI TaxID: 862238; scientific name: Naja nigricollis; NCBI TaxID: 8654; scientific name: Naja melanoleuca; NCBI TaxID: 8643; scientific name: Naja ashei; NCBI TaxID: 696811; scientific name: Naja annulifera; NCBI TaxID: 96794; scientific name: Bitis arietans; NCBI TaxID: 8692; scientific name: Bitis nasicornis; NCBI TaxID: 8695; scientific name: Naja anchietae; NCBI TaxID: 263737; scientific name: Naja pallida; NCBI TaxID: 8658; scientific name: Naja nigricincta; NCBI TaxID: 409860; scientific name: Bitis rhinoceros; NCBI TaxID: 715877; scientific name: Echis ocellatus; NCBI TaxID: 99586; scientific name: Bitis gabonica; NCBI TaxID: 8694; scientific name: Naja nubiae; NCBI TaxID: 186441; scientific name: Echis leucogaster; NCBI TaxID: 504457; scientific name: Naja mossambica; NCBI TaxID: 8644; scientific name: Dendroaspis jamesoni; NCBI TaxID: 8623;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-19 00:35:27	ID requested
⏵ 1	2022-10-17 06:10:37	announced

Dataset with its publication pending

submitter keyword: snakebite envenoming,snake venom, venomics

Andreas H.Laustsen
contact affiliation	Technical University of Denmark
contact email	ahola@bio.dtu.dk
lab head
CarolO'Brien
contact affiliation	Technical University of Denmark
contact email	cmaob@dtu.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD036161

PRIDE project URI

• PRIDE
  1. PXD036161
     1. Label: PRIDE project
     2. Name: High-throughput proteomics of the 26 medically most important elapids and vipers from sub-Saharan Africa