PXD036034-1

PXD036034 is an original dataset announced via ProteomeXchange.

Title	Cancer responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT)
Description	The vast majority of our knowledge regarding cancer radiobiology and the activation of radio-resistance mechanisms emerged from studies using external beam radiation therapy (EBRT). Yet, less is known about the cancer response to internal targeted radionuclide therapy (TRT). Our comparative proteomics and phosphoproteomics study analyzed response to TRT with lutetium-177 labeled minigastrin analogue [177Lu]Lu-PP-F11N (β- emitter) in comparison to EBRT (ɣ-rays) in CCKBR-positive cancer cells.
HostingRepository	PRIDE
AnnounceDate	2022-09-07
AnnouncementXML	Submission_2022-09-07_04:36:26.006.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michal Grzmil
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; acetylated residue; monohydroxylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-12 13:27:54	ID requested
⏵ 1	2022-09-07 04:36:26	announced
2	2023-11-14 08:57:51	announced	2023-11-14: Updated project metadata.

10.1186/S13045-022-01343-Y;

submitter keyword: Human, cancer, proteomics, phosphoproteomics, radioresistance, minigastrin

Michal Grzmil
contact affiliation	Paul Scherrer Institute Center for Radiopharmaceutical Sciences Forschungsstrasse 111 5232 Villigen PSI Switzerland
contact email	michal.grzmil@psi.ch
lab head
Michal Grzmil
contact affiliation	Paul Scherrer Institute Center for Radiopharmaceutical Sciences
contact email	michal.grzmil@psi.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/09/PXD036034

PRIDE project URI

• PRIDE
  1. PXD036034
     1. Label: PRIDE project
     2. Name: Cancer responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT)