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PXD036007-1

PXD036007 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDevelopmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers
DescriptionUsing CRISPR-Cas9 to tag endogenous remodeler subunits in Drosophila melanogaster S2 cells, we demonstrate that developmental gene transcription requires SWI/SNF-type complexes, primarily to maintain distal enhancer accessibility.
HostingRepositoryPRIDE
AnnounceDate2023-10-24
AnnouncementXMLSubmission_2023-10-24_11:22:55.467.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRichardImre
SpeciesList scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationListmethylthiolated residue; monohydroxylated residue; deamidated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-12 12:35:26ID requested
12023-10-24 11:22:56announced
22023-11-14 09:07:45announced2023-11-14: Updated project metadata.
32024-10-22 06:08:56announced2024-10-22: Updated project metadata.
Publication List
Hendy O, Serebreni L, Bergauer K, Muerdter F, Huber L, Nem, č, ko F, Stark A, Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers. Mol Cell, 82(19):3598-3612.e7(2022) [pubmed]
Keyword List
submitter keyword: Brd7,Chromatin Remodelers, SWI/SNF, Drosophila, Transcription
Contact List
AlexanderStark
contact affiliationIMP, Vienna Biocenter, Vienna, Austria
contact emailstark@starklab.org
lab head
RichardImre
contact affiliationIMBA Vienna
contact emailrichard.imre@imba.oeaw.ac.at
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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