PXD035723-2

PXD035723 is an original dataset announced via ProteomeXchange.

Title	Molecular basis for differential activation of p101 and p84 complexes of PI3Kg by Ras and GPCRs
Description	Using hydrogen deuterium exchange mass spectrometry, we reveal molecular differences between the two p110g-p84 and p110g-p101 complexes that explain their differential activation.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:25:22.012.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	John Burke
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	impact HD

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-02 02:18:49	ID requested
1	2023-03-09 17:52:28	announced
⏵ 2	2023-11-14 08:25:22	announced	2023-11-14: Updated project metadata.
3	2024-10-22 05:42:45	announced	2024-10-22: Updated project metadata.

submitter keyword: pi3kg, p101, ras, p110g, HDX-MS,HDX, gby

John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
lab head
John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD035723

PRIDE project URI

• PRIDE
  1. PXD035723
     1. Label: PRIDE project
     2. Name: Molecular basis for differential activation of p101 and p84 complexes of PI3Kg by Ras and GPCRs