PXD035331 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Data in support of TNF inhibition in experimental rotator cuff tear mouse model |
| Description | Musculoskeletal injuries related to the rotator cuff (RC) are frequent and account for up to 70% of shoulder pain problems. Lesions of the RC lead to weakness and pain (ref: Carr et al mfl) and untreated these lesions are acompanied by muscle degeneration modulated by inflammatory reactions that vary in intensity. Anti-inflammatory modalities such as NSAID and corticosteroids are commonly used as add ons to conservative treatment of RC tendon tears or RC tendon surgery, which are, however associated with high failure rates. The aim was to study the impact that a conventional TNF inhibitor and a super selective TNF inhibitor (Anti-TNF treatment) has on soft tissue inflammation and bone constituent parameters/connective tissue in a rotator cuff tear model. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-12_09:05:55.495.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Allan Stensballe |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2022-07-14 06:13:55 | ID requested | |
| ⏵ 1 | 2026-01-12 09:05:56 | announced | |
Publication List
| 10.1042/bsr20253559; |
| Aboo C, Lambertsen KL, Nasseri S, Ding M, Jensen PT, Linh Ta TM, Ditzel N, Schr, ø, der HD, Stensballe A, Hejb, ø, l EK, Frich LH, The effect of the nonselective TNF inhibitor etanercept and of the selective TNF inhibitor XPro1595 on lesioned supraspinatus muscle. Biosci Rep, 45(12):(2025) [pubmed] |
Keyword List
| submitter keyword: proteomics, rotator cuff, mouse |
Contact List
| Allan Stensballe |
|---|
| contact affiliation | Laboraotry for translational biomarkers and digital health |
| contact email | as@hst.aau.dk |
| lab head | |
| Allan Stensballe |
|---|
| contact affiliation | Aalborg University |
| contact email | as@hst.aau.dk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD035331 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035331
- Label: PRIDE project
- Name: Data in support of TNF inhibition in experimental rotator cuff tear mouse model
