PXD035259-1

PXD035259 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cell surface proteome profiling of cancer-associated fibroblast-induced myeloid-derived suppressor cells and related cell types
Description	Cancer-associated fibroblasts (CAF) promote immune suppression in the tumor microenvironment by polarizing monocytes to myeloid-derived suppressor cells (MDSC) that potently suppress T-cell function. Using a patient-derived coculture system, we profiled the cell surface proteome of CAF-induced MDSC to identify potential mechanism through which T-cell function is impaired.
HostingRepository	PRIDE
AnnounceDate	2024-01-04
AnnouncementXML	Submission_2024-01-04_08:02:54.774.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Carlo Ramil
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-11 13:55:03	ID requested
⏵ 1	2024-01-04 08:02:55	announced
2	2024-10-22 06:19:24	announced	2024-10-22: Updated project metadata.

Publication List

10.1080/2162402X.2023.2300882;

10.1080/2162402X.2023.2300882;

Keyword List

submitter keyword: MDSC, Stroma, Coculture,CAF, myeloid

submitter keyword: MDSC, Stroma, Coculture,CAF, myeloid

Contact List

An Chi
contact affiliation	Merck & Co., Inc.
contact email	an_chi@merck.com
lab head
Carlo Ramil
contact affiliation	Merck Research Laboratories
contact email	carlo.ramil@merck.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD035259
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD035259

PRIDE project URI

Repository Record List

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