PXD034951-1

PXD034951 is an original dataset announced via ProteomeXchange.

Title	Identification of mutated peptides based on the SNVs dataset derived from translatome
Description	We comprehensively investigating mutated peptide detection in HCT116 human cell line. We collected transcriptome and translatome data from HCT116, gather the sets of nsSNVs that are express in two different RNA level to construct two customized mutated protein libraries, in addition, a non-customized library was constructed utilizing nsSNVs downloaded from COSMIC database. MaxQuant was used to searched the libraries against shotgun MS data obtain from the same sample. Then, various characteristics of the detected mutated peptides were described, including identification number, identification overlap, and peptide quality.
HostingRepository	iProX
AnnounceDate	2022-06-28
AnnouncementXML	Submission_2023-06-01_18:56:16.307.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuting Liang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-28 18:21:06	ID requested
⏵ 1	2023-06-01 18:56:16	announced

Dataset with its publication pending

submitter keyword: Translatome, Transcriptome, Proteome, Single-nucleotide variant, Mutated peptides

Siqi Liu
contact affiliation	Beijing Genomics Instituion (BGI)-Shenzhen
contact email	siqiliu@genomics.cn
lab head
Yuting Liang
contact affiliation	Beijing Genomics Instituion (BGI)-Shenzhen
contact email	liangyuting@genomics.cn
dataset submitter

iProX dataset URI