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PXD034434-2

PXD034434 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFBL promotes cancer cell resistance to DNA damage by transcriptionally regulating BRCA1 via YBX1
DescriptionIn order to study the molecular mechanism of FBL in cells, this project constructed the full length of FBL into the SFB (S-Flag-SBP tag) vector, and constructed a stable cell line overexpressing FBL. Affinity chromatography combined with LC-MS/MS technology to screen FBL interacting proteins.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_09:04:16.771.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhenzhen Yan
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-06-09 14:27:22ID requested
12023-07-25 19:39:20announced
22023-11-14 09:04:23announced2023-11-14: Updated project metadata.
32024-10-22 05:57:51announced2024-10-22: Updated project metadata.
Publication List
Sun X, Gao C, Xu X, Li M, Zhao X, Wang Y, Wang Y, Zhang S, Yan Z, Liu X, Wu C, FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1. EMBO Rep, 24(9):e56230(2023) [pubmed]
Keyword List
submitter keyword: Human, HCT116 cells, nonoLC-MS/MS, FBL
Contact List
Chen Wu
contact affiliationHebei university
contact emailwuchen@hbu.edu.cn
lab head
Zhenzhen Yan
contact affiliationHebei University
contact emailyanzhzh@hbu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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