PXD034361-1

PXD034361 is an original dataset announced via ProteomeXchange.

Title	Concomitant targeting of viral and host methyltransferases is essential for attenuating SARS-CoV-2
Description	LC-MS/MS based investigation of protein abundance changes, induced by DZNep treatment in A549-ACE2 cell line (0.75 uM DZNep, vehicle PBS; 6h pre-treatment, harvested 24 h.p.i. with mock/SARS-CoV/SARS-CoV-2 at MOI 3) or primary human bronchial epithelial cells (NHBEs) (1.5 uM DZNep, vehicle PBS; 6h pre-treatment, harvested 36 h.p.i. with mock/SARS-CoV/SARS-CoV-2 at MOI 3), or by Tubercidin in A549-ACE2 cell line (1 uM Tubercidin, vehicle DMSO; 3h pre-treatment, harvested 24 h.p.i. with mock/SARS-CoV at MOI 0.01/SARS-CoV-2 at MOI 0.1).
HostingRepository	PRIDE
AnnounceDate	2022-06-28
AnnouncementXML	Submission_2022-06-28_08:15:35.525.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Valter Bergant
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-06 03:08:27	ID requested
⏵ 1	2022-06-28 08:15:35	announced

Dataset with its publication pending

submitter keyword: SARS-CoV-2, DZNep, Tubercidin, NHBE, A549, A549-ACE2

Andreas Pichlmair
contact affiliation	Immunopathology of Virus Infections Institute of Virology Technical University of Munich Schneckenburgerstr. 8 D-81675 Munich, Germany tel: +49 (0) 89 4140 9270
contact email	andreas.pichlmair@tum.de
lab head
Valter Bergant
contact affiliation	Institute of Virology, School of Medicine, Technical University of Munich (TUM), Munich, Germany
contact email	v.bergant@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/06/PXD034361

PRIDE project URI

• PRIDE
  1. PXD034361
     1. Label: PRIDE project
     2. Name: Concomitant targeting of viral and host methyltransferases is essential for attenuating SARS-CoV-2