PXD033969-1

PXD033969 is an original dataset announced via ProteomeXchange.

Title	Milk proteins as a feed restriction signature in dairy cows
Description	Milk production in dairy cows is affected by numerous factors, including diet. Feed restriction is known to have little impact on milk total protein content but its effect on the fine protein composition is still poorly documented. The objective of this study was to describe the effects of two feed restriction trials of different intensities on the milk protein composition of Holstein cows. One restriction trial was short and of high intensity (SH), the second was long and of moderate intensity (LM). Feed restriction decreased the milk protein yield for caseins under the LM trial and of all six major milk proteins under the SH trial. These decreased yields lead to lower concentrations of αs1-, αs2- and β-caseins during the SH trial. The milk proteome was affected as a function of restriction intensity. Among the 345 proteins identified eight varied under the LM trial and 160 under the SH trial. Ontology analyses revealed their implication in carbohydrate, lipid and protein metabolisms as well as in the immune system. These proteins reflected adaptations of the animal and mammary gland physiology to feed restriction and constituted a signature of this change.
HostingRepository	PRIDE
AnnounceDate	2022-11-10
AnnouncementXML	Submission_2022-11-10_02:34:21.335.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	LydieCorreia
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-18 07:29:31	ID requested
⏵ 1	2022-11-10 02:34:21	announced
2	2023-11-14 08:58:15	announced	2023-11-14: Updated project metadata.

submitter keyword: Milk proteins, cows, LC-MS/MS

Lydie Correia, INRAPAPPSO
contact affiliation	INRAE MICALIS PAPPSO
contact email	lydie.oliveira-correia@inrae.fr
lab head
LydieCorreia
contact affiliation	INRA PAPPSO
contact email	lydie.oliveira-correia@inra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD033969

PRIDE project URI

• PRIDE
  1. PXD033969
     1. Label: PRIDE project
     2. Name: Milk proteins as a feed restriction signature in dairy cows