PXD033785 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Label Free Quantification Mass Spectrometry Identifies Protein Markers of Chemoresistance in Serous Ovarian Cancer |
Description | Ovarian cancer is still the most lethal gynecological cancer, despite advances in patients’ strati-fication and treatment. Only about 80% of patients respond to the first line of treatment and many suffer a relapse with a treatment resistant disease. Here, we have identified three potential markers for chemoresistance using primary tumour samples. Moreover, we have shown their concurrent regulation in a chemoresistant cell line. This implies those cells as a useful model to study chemoresistance and to test novel drugs. |
HostingRepository | PRIDE |
AnnounceDate | 2023-05-10 |
AnnouncementXML | Submission_2023-05-10_13:42:33.086.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD033785 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | ParulMittal |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | maXis |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-09 05:44:01 | ID requested | |
⏵ 1 | 2023-05-10 13:42:33 | announced | |
2 | 2023-11-14 08:46:51 | announced | 2023-11-14: Updated project metadata. |
Publication List
Arentz G, Mittal P, Klingler-Hoffmann M, Condina MR, Ricciardelli C, Lokman NA, Kaur G, Oehler MK, Hoffmann P, Label-Free Quantification Mass Spectrometry Identifies Protein Markers of Chemotherapy Response in High-Grade Serous Ovarian Cancer. Cancers (Basel), 15(7):(2023) [pubmed] |
10.6019/PXD033785; |
Keyword List
submitter keyword: chemoresistance, mass-spectrometry, ovarian cancer |
Contact List
Prof PeterHoffmann |
contact affiliation | Lloyd Sansom Chair President Australasian Proteome Society Treasurer international HUPO Clinical Health Sciences Bradley Building, HB 8-28 North Terrace University of South Australia Adelaide, South Australia 5000 m: +61 434 079 108 |
contact email | peter.hoffmann@unisa.edu.au |
lab head | |
ParulMittal |
contact affiliation | Research associate |
contact email | pearl106@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033785
- Label: PRIDE project
- Name: Label Free Quantification Mass Spectrometry Identifies Protein Markers of Chemoresistance in Serous Ovarian Cancer