PXD033724-1
PXD033724 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Icariside II restores vascular smooth muscle cell contractile phenotype by enhancing focal adhesion signaling pathway in rat vascular remodeling model |
| Description | In this work, we investigated the pharmacological effects of ICS-II on VSMC phenotypic transition and reveal the underlying mechanisms through in vivo and in vitro experiments. Our results highlight the thera-peutic benefits of ICS-II targeting VSMC phenotypic transition and sup-port the potential of pharmacological strategies in CVD management. |
| HostingRepository | iProX |
| AnnounceDate | 2022-05-05 |
| AnnouncementXML | Submission_2022-05-05_18:41:01.111.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hao Wen |
| SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
| ModificationList | S-carboxamidomethyl-L-cysteine |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-05-05 18:40:43 | ID requested | |
| ⏵ 1 | 2022-05-05 18:41:01 | announced | |
| 2 | 2022-09-26 00:03:19 | announced | 2022-09-26: Update publication information. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Icariside II, Vascular smooth muscle cell, Phenotypic transition, Vascular remodeling, Herbal medicine |
Contact List
| Hao Wen | |
|---|---|
| contact affiliation | The First Hospital of China Medical University |
| contact email | wenhao@cmu.edu.cn |
| lab head | |
| Hao Wen | |
| contact affiliation | The First Hospital of China Medical University |
| contact email | wenhao@cmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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