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PXD033569-2

PXD033569 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLa protein plays its RNA chaperone function by binding with the mRNAs of target genes and participates the pathological process of ovarian cancer
DescriptionThe expression of La protein in A2780 ovarian cells was interfered by Lentivirus. In order to research the effect of La RNA interference on the expression of proteins in ovarian cancer A2780 cells, proteomic analysis conducted by TMT labeling and MS analysis was done in interference group (KD1) group and control group (NC) with 5 biological replicates in each group.
HostingRepositoryiProX
AnnounceDate2022-04-30
AnnouncementXMLSubmission_2022-09-28_19:47:12.128.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXuan Huang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-04-30 07:14:29ID requested
12022-04-30 07:14:47announced
22022-09-28 19:47:12announced2022-09-29: Update publication information.
Publication List
Huang X, Zhu J, Li Y, Yu Y, Tang J, La protein regulates protein expression by binding with the mRNAs of target genes and participates the pathological process of ovarian cancer. Front Oncol, 12():763480(2022) [pubmed]
Keyword List
submitter keyword: La protein, ovarian cancer, quantitative proteomics
Contact List
Jing Tang
contact affiliationObstetrics and Gynecology hospital of Fudan University
contact email1817@fckyy.org.cn
lab head
Xuan Huang
contact affiliationFudan University
contact email784587098@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI