PXD033542 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Bcl11b depleted and IL-15 stimulated αβ CD8+ T cells acquire a unique innate-like phenotype and are highly functional |
Description | Loss of BCL11B in human peripheral blood CD8+ T cells led to acquisition of an innate-like phenotype and the ability to efficiently lyse tumor cells either spontaneously via the NKp30/B7H6 axis or mediated by a GD2 antibody. The phenotype of BCL11B knock-out cells was investigated by characterization of surface marker profile, transcriptome, and proteome compared to control cells. |
HostingRepository | PRIDE |
AnnounceDate | 2022-12-13 |
AnnouncementXML | Submission_2022-12-13_08:07:37.369.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | ElkeHammer |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-28 01:50:35 | ID requested | |
⏵ 1 | 2022-12-13 08:07:37 | announced | |
2 | 2023-11-14 08:55:20 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: innateness, BCL11B knock-out,BCL11B, CD8+ T cells, IL-15 |
Contact List
ElkeHammer |
contact affiliation | Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald, Germany |
contact email | hammer@uni-greifswald.de |
lab head | |
ElkeHammer |
contact affiliation | Dept. of Functional Genomics |
contact email | hammer@uni-greifswald.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD033542 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033542
- Label: PRIDE project
- Name: Bcl11b depleted and IL-15 stimulated αβ CD8+ T cells acquire a unique innate-like phenotype and are highly functional