PXD033525 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The salivary proteome in relation to oral mucositis in autologous hematopoietic stem cell transplantation recipients: a labelled and label-free proteomics approach -DIAdata |
Description | Decreased salivary flow rates and/or changes in protein composition reported after autologous hematopoietic stem cell transplantation (ASCT) reduces the protective function of saliva. This might be associated with the development of oral mucositis (OM), an inflammation of the oral mucosa as a result of chemotherapy before ASCT which affects patients, quality of life and risk factor for systemic infections. In this study, a TMT-labelled proteomics experiment, a label-free quantification (LFQ) proteomics experiment and a DIA-MS proteomics experiment were used to identify differences in the salivary proteome between patients with ulcerative OM (uOM; WHO score 2) and those without (nOM). |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:05:27.785.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | An Staes |
SpeciesList | scientific name: human oral bacteria ensemble; NCBI TaxID: 150596; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-04-28 01:30:30 | ID requested | |
1 | 2023-07-10 04:26:46 | announced | |
⏵ 2 | 2023-11-14 07:05:28 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: LC-MS, TMT-labelled proteomics,TMT-MS, Label-free quantification, Saliva,Oral Mucositis, Autologous hematopoietic stem cell transplantation, Multiple Myeloma,DIA-MS |
Contact List
Nicole M.A. Blijlevens |
contact affiliation | Radboud university medical center, Radboud Institute for Health Sciences, Department of Hematology The Netherlands |
contact email | Nicole.Blijlevens@radboudumc.nl |
lab head | |
An Staes |
contact affiliation | Medical Protein Chemistry |
contact email | an.staes@vib-ugent.be |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD033525 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD033525
- Label: PRIDE project
- Name: The salivary proteome in relation to oral mucositis in autologous hematopoietic stem cell transplantation recipients: a labelled and label-free proteomics approach -DIAdata